Studies on the biosynthesis of podophyllotoxin:synthesis of labelled yatein and matairesinol, two potential precursors of podophyllotoxin
Podophyllotoxin, a naturally occurring lignan isolated from several species of Podophyllum, is used as a precursor to the clinical chemotherapeutic agents teniposide and etoposide. The biosynthesis of podophyllotoxin is not fully understood, but its optical activity, like that of most lignans, is su...
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Format: | Others |
Language: | en |
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Virginia Tech
2014
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Online Access: | http://hdl.handle.net/10919/44847 http://scholar.lib.vt.edu/theses/available/etd-09192009-040255/ |