Development of Potent and Selective Bivalent Inhibitors for Protein Kinases Utilizing Phage Display

Protein kinases function as key regulators in a variety of signaling pathways by executing the phosphorylation of a variety of protein substrates. Perturbation in the activity of numerous proteins kinases has been implicated in a large number of diseases including cancer, diabetes, inflammation and...

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Bibliographic Details
Main Author: Lamba, Vandana
Other Authors: Ghosh, Indraneel
Language:en
Published: The University of Arizona. 2012
Subjects:
Online Access:http://hdl.handle.net/10150/265559