Insulin receptor substrate 1 is a substrate of the Pim protein kinases

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

The Pim family of serine/threonine protein kinases (Pim 1, 2, and 3) contribute to cellular transformation by regulating glucose metabolism, protein synthesis, and mitochondrial oxidative phosphorylation. Drugs targeting the Pim protein kinases are being tested in phase I/II clinical trials for the...

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Bibliographic Details
Main Authors: Song, Jin H., Padi, Sathish K. R., Luevano, Libia A., Minden, Mark D., DeAngelo, Daniel J., Hardiman, Gary, Ball, Lauren E., Warfel, Noel A., Kraft, Andrew S.
Other Authors: Univ Arizona, Dept Cellular & Mol Med
Language:en
Published: IMPACT JOURNALS LLC 2016
Subjects:
insulin
IGF1
IRS1
Pim kinase
Pim kinase inhibitor
Online Access:http://hdl.handle.net/10150/614947
http://arizona.openrepository.com/arizona/handle/10150/614947

Internet

http://hdl.handle.net/10150/614947
http://arizona.openrepository.com/arizona/handle/10150/614947

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