Mutation-Specific Calcium Dysregulation in Hypertrophic Cardiomyopathy

As the genetic causes of Hypertrophic Cardiomyopathy (HCM) have become widely recognized, considerable lag in the development of targeted therapeutics has limited interventions to symptom palliation. This is in part due to an oft-noted finding that similar point mutations within myofilament proteins...

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Bibliographic Details
Main Author: Lehman, Sarah
Other Authors: Tardiff, Jil C.
Language:en_US
Published: The University of Arizona. 2018
Subjects:
Online Access:http://hdl.handle.net/10150/626641
http://arizona.openrepository.com/arizona/handle/10150/626641