Studies of the trafficking of the insulin-responsive glucose transporter, GLUT4, in 3T3-L1 adipocytes
The translocation of GLUT4 from intracellular stores to the plasma membrane in response to insulin accounts for the large insulin-mediated glucose uptake in muscle and fat tissue. A defect of this translocation mechanism is evident in individuals with insulin resistance and type 2 diabetes. Hence, u...
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University of Glasgow
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366195 |