The role of Rab GTPases in osteoclasts
Bisphosphonates are the most widely prescribed anti-resorptive agents and work by preventing the post-translational modification (prenylation) of small GTPases in osteoclasts, subsequently leading to cell death by apoptosis. Phosphonocarboxylate analogues of bisphosphonates also have anti-resorptiv...
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University of Aberdeen
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509139 |