Proteomic and molecular characterisation of TRAIL-induced signalling complexes
TRAIL selectively induces apoptosis in cancerous cells through the formation of the death-inducing signalling complex (DISC). Apoptosis can progress through either a Type I (direct procaspase-3 cleavage) or Type II (Bid cleavage) route. However, factors acting at the DISC, which may determine the se...
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University of Leicester
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551898 |