Informative sequence-based models for fragment distributions in ChIP-seq, RNA-seq and ChIP-chip data

Many high throughput sequencing protocols for RNA and DNA require that the polynucleic acid is fragmented so that the identity of a limited number of nucleic acids of one or both of the ends of the fragments can be determined by sequencing. The nucleic acid sequence allows the fragment to be located...

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Bibliographic Details
Main Author: Dyer, Nigel
Published: University of Warwick 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.560250