Synthesis and properties of nucleic acid duplexes and quadruplexes containing 3'-S-phosphorothiolate linkages
3'-Thiopurine 2'-deoxynucleosides have been incorporated into model oligodeoxynucleotides (DONs) thus giving rise to ODNs that consist of the 3- S-phosporothiolate (3'-sp) linkage. Due to the complex chemical manipulations implicated, the preparation of such analogues has been scarcel...
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University of Liverpool
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569181 |