Heterotrimeric G-protein interactions and activation in chemokine receptor 5 signalling

Activation of the G-protein coupled receptor (GPCR) chemokine receptor 5 (CCR5) has been shown to result in activation of the Gαi family of heterotrimeric G-proteins. However, little is currently known about the temporal characteristics of G-protein heterotrimer activation by CCR5. Furthermore, this...

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Bibliographic Details
Main Author: Kerr, Jason Stuart
Published: University of East Anglia 2010
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569309