Novel oxetane-containing spirocycles and peptidomimetics

This thesis describes work focused on the use of oxetane rings as isosteres and incorporation of this functional group into pharmaceutically relevant scaffolds. Chapter 1 describes work directed towards the synthesis of 1,5-dioxaspiro[2.3]hexanes via three different strategies, namely ring-closure t...

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Bibliographic Details
Main Author: Powell, Nicola Helen
Published: University of Warwick 2014
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640974