Key enzymes of sphingolipid biosynthesis
Serine palmitoyl transferase (SPT) catalyses the first and rate limiting step of sphingolipid biosynthesis; a decarboxylative, Claisen condensation of the amino acid L-serine and the long chain fatty acid palmitoyl CoA to produce the first sphingolipid precursor 3-ketodihydrosphingosine. We propose...
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University of Edinburgh
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664110 |