Solubilisation and characterisation of G-protein-coupled receptors using styrene maleic acid polymer

Detergent-free solubilisation using a polymer of styrene maleic acid (SMA) has proven useful in the study of membrane proteins. SMA was employed to solubilise G-protein-coupled receptors (GPCRs) from mammalian cells, into SMA lipid particles (SMALPs). Optimal SMALP solubilisation conditions were det...

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Bibliographic Details
Main Author: Charlton, Jack
Published: University of Birmingham 2016
Subjects:
500
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681124