An NMR study into the structure and interactions of the transmembrane domains of Neu and PDGFβ receptor tyrosine kinases

Receptor tyrosine kinases (RTKs) form a medically important class of membrane proteins whose malfunction as signalling entities has been reported as the cause of a large number of diseases. The structure and dynamics of the transmembrane domain (TM) of these receptors is central to their role in cel...

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Bibliographic Details
Main Author: Hasan, Muhammad
Published: University of Warwick 2015
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685186