Functional analysis of the osteoarthritis susceptibility loci marked by the polymorphisms rs10492367 and rs9350591

Approximately 8.5 million people in the UK are affected by osteoarthritis (OA), a multifactorial, polygenic disease characterised by articular cartilage loss. In 2012, the arcOGEN Consortium reported on the largest OA genome-wide association scan (GWAS) to date, in which five regions of the genome w...

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Bibliographic Details
Main Author: Johnson, Katherine
Published: University of Newcastle upon Tyne 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701148