The discovery of small-molecule inhibitors of ERK5 for the treatment of cancer
Mitogen-activated protein kinases (MAPKs) play an essential role in the transduction of extracellular signals to cytoplasmic and nuclear effectors. MAP kinase kinases (MEKs/MAPKKs) represent protein kinases upstream of MAPKs, critically controlling cellular proliferation and apoptosis. Mitogen/extra...
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University of Newcastle upon Tyne
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.703156 |