Genetic and biological markers of severity in sickle cell disease

Sickle cell disease (SCD) is remarkable for the variability of its phenotype despite its genetic simplicity, with family and population studies indicating a strong genetic influence. The best characterised genetic modifiers are genes controlling HbF levels and co-inheritance of alpha-thalassaemia. O...

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Bibliographic Details
Main Author: Drasar, Emma Rachel
Other Authors: Thein, Swee Lay ; Vasavda, Nisha ; Menzel, Stephan
Published: King's College London (University of London) 2014
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718514