An evaluation of in vitro models for the assessment of mitochondrial toxicity within Drug Induced Liver Injury (DILI)

Drug Induced Liver Injury (DILI) is of major concern to both clinicians and the pharmaceutical industry due to the attrition of lead compounds during preclinical development and the incidence of hepatotoxicity and/or the withdrawal of drugs post marketing. It has been hypothesised that drug-induced...

Full description

Bibliographic Details
Main Author: Douglas, O.
Other Authors: Chadwick, A.
Published: University of Liverpool 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733950