Probing the Conformational Dynamics of Human Glucokinase
Human glucokinase is a 52 kDa single polypeptide chain containing 465 amino acids and a single binding site. It catalyzes the ATP dependent phosphorylation of glucose in the beta pancreatic cells, which ultimately serves as the glucose sensor. In contrast to most monomeric enzymes that show characte...
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Language: | English English |
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Florida State University
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Online Access: | http://purl.flvc.org/fsu/fd/FSU_migr_etd-5911 |