Manipulating Somatic Cells to Remove Barriers in Induced Pluripotent Stem Cell Reprogramming

Development leads unidirectionally towards a more restricted cell fate that is usually stable. However, it has been proven that developmental systems are reversible by the success of animal cloning of a differentiated somatic genome through somatic cell nuclear transfer (SCNT). Recently, reprogrammi...

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Bibliographic Details
Main Author: Chung, Julia
Other Authors: Eggan, Kevin Carl
Language:en_US
Published: Harvard University 2013
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard:10772
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11156809