Manipulating Somatic Cells to Remove Barriers in Induced Pluripotent Stem Cell Reprogramming
Development leads unidirectionally towards a more restricted cell fate that is usually stable. However, it has been proven that developmental systems are reversible by the success of animal cloning of a differentiated somatic genome through somatic cell nuclear transfer (SCNT). Recently, reprogrammi...
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Language: | en_US |
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Harvard University
2013
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Online Access: | http://dissertations.umi.com/gsas.harvard:10772 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11156809 |