Interactions of quinoline antimalarial drugs with ferrihaem : structural and kinetic insights into the inhibition of malaria pigment formation

Thesis (PhD)--Stellenbosch University, 2013. === ENGLISH ABSTRACT: The work in this dissertation provides structural and kinetic insight into the mechanism of action of quinoline antimalarial drugs which may aid rational drug design. Quinoline antimalarial drug-ferrihaem (Fe(III)PPIX) complexes we...

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Bibliographic Details
Main Author: Gildenhuys, Johandie
Other Authors: De Villiers-Chen, Katherine
Format: Others
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2013
Subjects:
Online Access:http://hdl.handle.net/10019.1/85621