The measurement of glomerular basement membrane components and glycated albumin as improved markers of incipient diabetic nephropathy.
Diabetes causes early structural changes to the glomerular basement membrane (GBM), which alters its function and leads to loss of protein in urine. Formation of advanced glycation endproducts (AGEs) is one mechanism proposed to be responsible for the structural changes to the GBM. AGEs are thought...
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Language: | en |
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2012
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Online Access: | http://hdl.handle.net/10413/5375 |