| Summary: | In dermatology, as in many other fields of medicine, we often have to deal with wounds and their healing. In the submitted study that is based on research carried out in the Department of Dermatology of the Military Hospital in Olomouc, Czech Republic we want to explore healing of chronic wounds, which represent a serious medical, social and economic problem. We dealt with diagnosing, treatment and prevention of chronic wounds in connection with the application of the new wound dressing and various methods of treatment. The aim of this study is to summarize knowledge and experience gained with healing of chronic wounds, to draw the attention to the serious conditions of diabetic and neoplastic ulcerations as well as present new possibilities in the systemic therapy. We carried out clinical examination and laboratory testing of the bio-active dressing influence on the chronic wounds markers production (MMP-2, MMP-9 a TNF-α) and on wound-healing. In laboratory testing we followed the sandwich ELISA method; during the clinical examination we evaluated the wound and its surrounding, the pain, microbiological colonisation and the contentedness with the therapy in the patients' and in the doctors' evaluations. The dressing used positively influenced the character of the wound and its surrounding, its...
|
|---|
