Design and synthesis of 3-[N-(cyclopropylmethyl) amino]-7-(methoxy or hydroxy)-2, 2-dimethyl-1-tetralone analogs as potential opioid receptor antagonists
A series of 3-aminotetralins were synthesized as potential opioid antagonists. Each proposed target compound was based on a 3-(mono- or dialkylamino )-7 -(hydroxy or methoxy)-2, 2-dimethyl-1-tetralone parent structure. Three synthetic schemes were developed utilizing the common intermediate, ethyl3-...
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Scholarly Commons
2004
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Online Access: | https://scholarlycommons.pacific.edu/uop_etds/591 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1590&context=uop_etds |