Design and synthesis of 3-[N-(cyclopropylmethyl) amino]-7-(methoxy or hydroxy)-2, 2-dimethyl-1-tetralone analogs as potential opioid receptor antagonists

A series of 3-aminotetralins were synthesized as potential opioid antagonists. Each proposed target compound was based on a 3-(mono- or dialkylamino )-7 -(hydroxy or methoxy)-2, 2-dimethyl-1-tetralone parent structure. Three synthetic schemes were developed utilizing the common intermediate, ethyl3-...

Full description

Bibliographic Details
Main Author: Williams, Brett H.
Format: Others
Published: Scholarly Commons 2004
Subjects:
Online Access:https://scholarlycommons.pacific.edu/uop_etds/591
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1590&context=uop_etds