Degradation of human alpha- and beta-defensins by culture supernatants of Porphyromonas gingivalis
Porphyromonas gingivalis produces proteases capable of degrading cytokines, host heme proteins, and some antimicrobial peptides. In this work, I show that P. gingivalis culture supernatants fully or partially degrade human neutrophil peptide alpha-defensins and human beta-defensins after 30 minutes....
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Format: | Others |
Language: | English |
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University of Iowa
2010
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Online Access: | https://ir.uiowa.edu/etd/651 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1836&context=etd |