The Effects of Conformation and Aggregation on the Pharmaceutical Chemistry Properties of Lipopeptide (Daptomycin)
The objectives of this research were to identify the individual ionization constants (pKa values) of lipopeptide (daptomycin), evaluate the factors of pH, concentration, temperature, and calcium ions on daptomycin aggregation in aqueous solutions, and elucidate th...
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| Format: | Others |
| Language: | English |
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University of Iowa
2013
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| Online Access: | https://ir.uiowa.edu/etd/4902 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=4859&context=etd |