Probing the PCB metabolome: metabolism of chiral and non-chiral polychlorinated biphenyls to chiral hydroxylated metabolites in humans and rats

Polychlorinated biphenyls (PCBs) continue to pose a health concern because of their predominance in the diet and air as well as in environmental samples and humans. PCB congeners with 3 or 4 chlorine substituents in ortho position have been associated with neurodevelopmental disorders. Hydroxylated...

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Bibliographic Details
Main Author: Uwimana, Eric
Other Authors: Lehmler, Hans-Joachim
Format: Others
Language:English
Published: University of Iowa 2018
Subjects:
Online Access:https://ir.uiowa.edu/etd/6657
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8156&context=etd