Fumarate Activation and Kinetic Solvent Isotope Effects as Probes of the NAD-Malic Enzyme Reaction
The kinetic mechanism of activation of the NAD-malic enzyme by fumarate and the transition state structure for the oxidation malate for the NAD-malic enzyme reaction have been studied. Fumarate exerts its activating effect by decreasing the off-rate for malate from the E:Mg:malate and E:Mg:NAD:malat...
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| Format: | Others |
| Language: | English |
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University of North Texas
1992
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| Online Access: | https://digital.library.unt.edu/ark:/67531/metadc278864/ |