Derivation and Characterization of Pax7 Positive Skeletal Muscle Precursor Cells from Control and HGPS-derived induced Pluripotent Stem Cells

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder associated with premature aging in various tissues and organs of the afflicted individuals, including accelerated skeletal muscle atrophy. Classical HGPS manifests due to single-base substitution in the LAMNA gene which encodes L...

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Bibliographic Details
Main Author: Kocharyan, Avetik
Other Authors: Kates, Ilona Sylvia
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2018
Subjects:
Online Access:http://hdl.handle.net/10393/37517
http://dx.doi.org/10.20381/ruor-21786