Derivation and Characterization of Pax7 Positive Skeletal Muscle Precursor Cells from Control and HGPS-derived induced Pluripotent Stem Cells
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder associated with premature aging in various tissues and organs of the afflicted individuals, including accelerated skeletal muscle atrophy. Classical HGPS manifests due to single-base substitution in the LAMNA gene which encodes L...
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Format: | Others |
Language: | en |
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Université d'Ottawa / University of Ottawa
2018
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Online Access: | http://hdl.handle.net/10393/37517 http://dx.doi.org/10.20381/ruor-21786 |