Capsaicin as an amphipathic modulator of NaV1.5 mechanosensitivity
SCN5A-encoded NaV1.5 is a voltage-gated Na+ channel that drives the electrical excitability of cardiac myocytes and contributes to slow waves of the human gastrointestinal smooth muscle cells. NaV1.5 is mechanosensitive: mechanical force modulates several facets of NaV1.5’s voltage-gated function, a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor and Francis Ltd.
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |