Haplotype-based inference of the distribution of fitness effects

Recent genome sequencing studies with large sample sizes in humans have discovered a vast quantity of low-frequency variants, providing an important source of information to analyze how selection is acting on human genetic variation. In order to estimate the strength of natural selection acting on l...

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Bibliographic Details
Main Authors: Lohmueller, K.E (Author), Novembre, J. (Author), Ortega-Del Vecchyo, D. (Author)
Format: Article
Published: NLM (Medline) 2022
Online Access:View Fulltext in Publisher