Altered basal forebrain BOLD signal variability at rest in posttraumatic stress disorder: A potential candidate vulnerability mechanism for neurodegeneration in PTSD

Altered basal forebrain BOLD signal variability at rest in posttraumatic stress disorder: A potential candidate vulnerability mechanism for neurodegeneration in PTSD

Individuals with posttraumatic stress disorder (PTSD) are at increased risk for the development of various forms of dementia. Nevertheless, the neuropathological link between PTSD and neurodegeneration remains unclear. Degeneration of the human basal forebrain constitutes a pathological hallmark of...

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Bibliographic Details
Main Authors: Densmore, M. (Author), Lanius, R.A (Author), Makris, N. (Author), McKinnon, M.C (Author), Olivé, I. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
alprazolam
amfebutamone
amitriptyline
amnesia
amygdala
Article
basal forebrain
Basal Forebrain
BOLD signal
cholinergic system
citalopram
clonazepam
complication
connectome
Connectome
controlled study
degenerative disease
dexamphetamine
diagnostic imaging
diazepam
dissociative disorder
Dissociative Disorders
dissociative subtype
extended amygdaloid area
female
fluoxetine
fluvoxamine
functional magnetic resonance imaging
haloperidol
hemodynamics
human
Humans
local BOLD hemodynamic signal variability
lorazepam
loxapine
Magnetic Resonance Imaging
major clinical study
male
methylphenidate
moclobemide
nerve degeneration
neurodegenerative illnesses
nuclear magnetic resonance imaging
nucleus accumbens
olanzapine
outcome assessment
paroxetine
pathology
pathophysiology
posttraumatic stress disorder
protriptyline
quetiapine
resting-state functional magnetic resonance imaging
risperidone
sertraline
Stress Disorders, Post-Traumatic
temazepam
trazodone
venlafaxine
zopiclone
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