EGFR amplification and expression in oral squamous cell carcinoma in young adults

EGFR amplification and expression in oral squamous cell carcinoma in young adults

The aim of this study was to investigate epidermal growth factor receptor (EGFR) gene alterations in two groups of patients with oral squamous cell carcinoma (OSCC) (a test group of subjects aged ≤40 years and a control group of subjects aged ≥50 years) and to associate the results with EGFR immunos...

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Bibliographic Details
Main Authors: Begnami, M.D (Author), Calsavara, V.F (Author), Costa, V. (Author), Coutinho-Camillo, C.M (Author), Kaminagakura, E. (Author), Kowalski, L.P (Author), Neves, J.I (Author)
Format: Article
Language:English
Published: Churchill Livingstone 2018
Subjects:
adult
Adult
aged
Aged
Aged, 80 and over
Article
cancer prognosis
cancer staging
cancer survival
Carcinoma, Squamous Cell
case control study
Case-Control Studies
child
Child
clinical article
controlled study
disease exacerbation
disease free survival
Disease Progression
EGFR gene
EGFR protein, human
epidermal growth factor receptor
ErbB Receptors
female
Female
fluorescence in situ hybridization
gene amplification
Gene Amplification
gene expression
gene mutation
gene overexpression
genetics
histopathology
human
Humans
immunohistochemistry
Immunohistochemistry
In Situ Hybridization, Fluorescence
male
Male
middle aged
Middle Aged
Mouth Neoplasms
mouth squamous cell carcinoma
mouth tumor
Neoplasm Staging
oral cancer
overall survival
pathology
prognosis
Prognosis
Retrospective Studies
retrospective study
squamous cell carcinoma
survival rate
Survival Rate
Tissue Array Analysis
tissue microarray
very elderly
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