Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands

Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands

Objectives: In 2010, a new subtype of salivary gland cancer (SGC), (mammary analogue) secretory carcinoma (SC), was defined, characterized by the ETV6-NTRK3 fusion gene. As clinical behavior and outcome data of this histological subtype tumor are still sparse, we aimed to describe the clinicopatholo...

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Bibliographic Details
Main Authors: Bloemena, E. (Author), Boon, E. (Author), Flucke, U.E (Author), Groenen, P.J.T.A (Author), Kaanders, J.H.A.M (Author), Meeuwis, C.A (Author), Merkx, M.A.W (Author), Slootweg, P.J (Author), Smit, L.A (Author), Takes, R.P (Author), Valstar, M.H (Author), van der Graaf, W.T.A (Author), van Herpen, C.M.L (Author), Willems, S.M (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2018
Subjects:
adult
Adult
aged
Aged
Aged, 80 and over
Article
cancer diagnosis
cancer radiotherapy
cancer recurrence
cancer staging
cancer surgery
clinical article
controlled study
disease duration
disease free survival
ETV6-NTRK3
ETV6-NTRK3 fusion protein, human
female
Female
follow up
fusion gene
Gene Fusion
genetics
Head and Neck Neoplasms
human
Humans
lymph node metastasis
male
Male
Mammary analogue secretory carcinoma
MASC
middle aged
Middle Aged
neck dissection
Neoplasm Recurrence, Local
Oncogene Proteins, Fusion
oncoprotein
outcome assessment
overall survival
pathology
priority journal
Prognosis
prospective study
retrospective study
reverse transcription polymerase chain reaction
salivary gland carcinoma
Salivary gland neoplasms
Salivary Gland Neoplasms
salivary gland tumor
Secretory carcinoma
survival analysis
Survival Analysis
transcription factor ETV6
tumor localization
tumor recurrence
very elderly
young adult
Young Adult
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