Shared genetic and epigenetic mechanisms between chronic periodontitis and oral squamous cell carcinoma

Shared genetic and epigenetic mechanisms between chronic periodontitis and oral squamous cell carcinoma

Objectives: To analyze bioinformatic datasets for detecting genetic and epigenetic mechanisms shared by chronic periodontitis (CP) and oral squamous cell carcinoma (OSCC). Materials and methods: Datasets from GEO and TCGA databases reporting mRNAs, miRNAs or methylation expression in human CP and OS...

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Bibliographic Details
Main Authors: Acharya, A. (Author), Deng, Y. (Author), Haak, R. (Author), Hu, X. (Author), Li, H. (Author), Li, S. (Author), Liu, X. (Author), Pan, H. (Author), Savkovic, V. (Author), Schmalz, G. (Author), Schmidt, J. (Author), Shang, R. (Author), Shang, W. (Author), Wu, N. (Author), Xu, C. (Author), Yu, Y. (Author), Zhou, Y. (Author), Ziebolz, D. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2018
Subjects:
Article
biology
cancer prognosis
chemokine receptor
chronic periodontitis
Chronic periodontitis
Chronic Periodontitis
Computational Biology
controlled study
Datasets as Topic
DNA methylation
DNA Methylation
epidermal growth factor receptor
Epigenesis, Genetic
epigenetics
epithelial mesenchymal transition
gene expression
gene expression profiling
Gene Expression Profiling
gene expression regulation
Gene Expression Regulation, Neoplastic
genetic analysis
genetic epigenesis
genetics
human
human tissue
Humans
information processing
messenger RNA
microRNA
microRNA 375
miRNA
Mouth Neoplasms
mouth squamous cell carcinoma
mouth tumor
mRNA
Oral squamous cell carcinoma
pathology
priority journal
protein protein interaction
Regulatory network
signal transduction
Signal Transduction
Squamous Cell Carcinoma of Head and Neck
vasculotropin receptor 1
vasculotropin receptor 2
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