The irradiated human mandible: A quantitative study on bone vascularity

The irradiated human mandible: A quantitative study on bone vascularity

Objectives: Hypovascularisation is thought to play an important role in the pathogenesis of osteoradionecrosis. The objective of this study was to assess the microvascular system in the irradiated mandibular bone marrow. Materials and methods: Mandibular bone biopsies were taken from 20 irradiated p...

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Bibliographic Details
Main Authors: Bloemena, E. (Author), Bravenboer, N. (Author), Dekker, H. (Author), Rietveld, D.H.F (Author), Schulten, E.A.J.M (Author), ten Bruggenkate, C.M (Author), van Dijk, D. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2018
Subjects:
adult
Adult
adverse event
aged
Aged
amoxicillin
antibiotic prophylaxis
Article
biopsy
Biopsy
blood vessel diameter
bone biopsy
bone marrow
Bone Marrow
bone necrosis
bone vascularity
case control study
Case-Control Studies
CD34 antibody
clavulanic acid
clinical article
controlled study
Dose-Response Relationship, Radiation
edentulousness
endothelium cell
female
Female
Head and Neck Neoplasms
head and neck tumor
human
human tissue
Humans
intensity modulated radiation therapy
irradiation
male
Male
mandible
Mandible
mandible osteotomy
Mandibular Osteotomy
Microvascular network
Microvasculature
Microvessel
middle aged
Middle Aged
musculoskeletal system parameters
Oral cancer
Osteoradionecrosis
pathology
priority journal
quantitative study
Radiation Dosage
radiation dose
radiation response
Radiotherapy
Radiotherapy, Intensity-Modulated
randomized controlled trial
single drug dose
time factor
Time Factors
tooth implantation
vascular area fraction
vascular density
vascularization
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