Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly

Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly

Parkinson’s disease (PD) is a progressive neurodegenerative disorder for which there is no successful prevention or intervention. The pathological hallmark for PD involves the self-assembly of functional Alpha-Synuclein (αS) into non-functional amyloid structures. One of the potential therapeutic in...

Full description

Bibliographic Details
Main Authors: Ahmed, J. (Author), Ball, T.D (Author), Bassil, M.M (Author), Donnelly, C.M (Author), Fitch, T.C (Author), Horowitz, S. (Author), Joseph, J.A (Author), Kumar, S. (Author), Ledreux, A. (Author), Paredes, D. (Author), Qin, Y. (Author), Son, A. (Author), Zhang, C. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items