In vivo expression of proteases and protease inhibitor, a serpin, by periodontal pathogens at teeth and implants

In vivo expression of proteases and protease inhibitor, a serpin, by periodontal pathogens at teeth and implants

Porphyromonas gingivalis and Tannerella forsythia secrete proteases, gingipains and KLIKK-proteases. In addition, T. forsythia produces a serpin (miropin) with broad inhibitory spectrum. The aim of this pilot study was to determine the level of expression of miropin and individual proteases in vivo...

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Bibliographic Details
Main Authors: Eckert, M. (Author), Eick, S. (Author), Mizgalska, D. (Author), Potempa, J. (Author), Sculean, A. (Author), Stavropoulos, A. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Ltd 2018
Subjects:
Aggregatibacter actinomycetemcomitans
Article
bacterial count
bacterial gene
bacterial proteases
bacterial protein
Bacterial Proteins
biofilm
Biofilms
biological marker
Biomarkers
biosynthesis
chemistry
clinical article
comparative study
complementary DNA
Dental Implants
disease association
disease severity
DNA extraction
DNA RNA hybridization
enzyme linked immunosorbent assay
enzymology
gene expression
gene expression regulation
Gene Expression Regulation, Bacterial
Genes, Bacterial
genetic code
genetics
Gingival Crevicular Fluid
gingivitis
Gingivitis
human
Humans
in vivo study
interleukin 10
interleukin 1beta
interleukin 8
Interleukin-10
Interleukin-1beta
Interleukin-8
medical record
messenger RNA
metabolism
microbiology
miropin
mucosa inflammation
Mucositis
nonhuman
pathogenicity
peptide hydrolase
Peptide Hydrolases
peri-implant disease
periimplantitis
Peri-Implantitis
periodontal disease
periodontitis
Periodontitis
Pilot Projects
pilot study
Porphyromonas gingivalis
Protease Inhibitors
proteinase
proteinase inhibitor
real time polymerase chain reaction
reverse transcription polymerase chain reaction
RNA extraction
RNA, Messenger
serine proteinase inhibitor
Serpins
Sweden
Tannerella forsythia
tooth implant
Treponema denticola
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