Tannerella forsythia-produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes

The periodontal pathogen Tannerella forsythia has the unique ability to produce methylglyoxal (MGO), an electrophilic compound which can covalently modify amino acid side chains and generate inflammatory adducts known as advanced glycation endproducts (AGEs). In periodontitis, concentrations of MGO...

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Bibliographic Details
Main Authors: Browne, R.W (Author), Genco, R.J (Author), Honma, K. (Author), LaMonte, M. (Author), Li, M. (Author), Settem, R.P (Author), Shankar, M. (Author), Sharma, A. (Author), Xu, D. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Ltd 2018
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