Single-Fluorescence ATP Sensor Based on Fluorescence Resonance Energy Transfer Reveals Role of Antibiotic-Induced ATP Perturbation in Mycobacterial Killing

The rapid emergence of multidrug-resistant/extensively drug-resistant tuberculosis (TB) is responsible for treatment failure in patients with TB and significantly endangers global public health. Recently, bioenergetics has become a new paradigm for anti-TB drug discovery and is based on the link bet...

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Bibliographic Details
Main Authors: Chen, Y. (Author), Feng, S. (Author), Li, J. (Author), Liang, L. (Author), Liang, W. (Author), Lin, D. (Author), Luo, W. (Author), Tian, G.-B (Author), Zhao, H. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2022
Subjects:
ATP
Online Access:View Fulltext in Publisher