$Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura$

Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura

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Background: Muntingia calabura L. (family Muntingiaceae), commonly known as Jamaican cherry or kerukup siam in Malaysia, is used traditionally to treat various ailments. The aim of this study is to elucidate the possible underlying gastroprotective mechanisms of ethyl acetate fraction (EAF) of Munti...

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Bibliographic Details
Main Authors:	Abdullah, M.N.H (Author), Ahmad, Z. (Author), Azemi, A.K (Author), Balan, T. (Author), Desa, M.N.M (Author), Mohtarrudin, N. (Author), Omar, M.H (Author), Salleh, M.Z (Author), Teh, L.K (Author), Zakaria, Z.A (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd. 2016
Subjects:	acetic acid ethyl ester alcohol angiosperm Angiosperms animal animal experiment animal model animal tissue Animals antioxidant Antioxidant Antioxidants Antisecretory antiulcer agent Anti-Ulcer Agents Article blood catalase chemistry controlled study Dinoprostone disease model Disease Models, Animal drug effects Fraction fractionation gallic acid Gallic acid Gallic Acid Gastric Mucosa Gastric ulcer gastrointestinal mucosa protective agent glutathione high performance liquid chromatography limit of quantitation male Male malonaldehyde Malondialdehyde metabolism mucus Mucus Muntingia calabura Muntingia calabura extract n ethylmaleimide n(g) nitroarginine methyl ester nitric oxide Nitric oxide Nitric Oxide nonhuman oxidative stress Oxidative Stress pathology pH phytotherapy Phytotherapy plant extract Plant Extracts plant leaf Plant Leaves Prostaglandin prostaglandin E2 protein content pylorus ligation induced gastric ulcer quercetin Quercetin ranitidine rat Rats, Sprague-Dawley Sprague Dawley rat stomach Stomach stomach content stomach mucosa stomach protection stomach ulcer Stomach Ulcer Sulfhydryl compound superoxide dismutase thiol derivative tissue homogenate unclassified drug
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Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura

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