Universally valid reduction of multiscale stochastic biochemical systems using simple non-elementary propensities

Universally valid reduction of multiscale stochastic biochemical systems using simple non-elementary propensities

Biochemical systems consist of numerous elementary reactions governed by the law of mass action. However, experimentally characterizing all the elementary reactions is nearly impossible. Thus, over a century, their deterministic models that typically contain rapid reversible bindings have been simpl...

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Bibliographic Details
Main Authors: Hong, H. (Author), Kim, J.K (Author), Song, Y.M (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
algorithm
Algorithms
Article
biochemical analysis
biological model
biology
cell communication
Cell Communication
cell cycle
Cell Cycle
chemical binding
chemical phenomena
Circadian Clocks
circadian rhythm
Computational Biology
computer simulation
Computer Simulation
conceptual framework
gene control
human
Humans
kinetics
Kinetics
Markov chain
Michaelis Menten kinetics
Models, Biological
molecular dynamics
Morrison equation
procedures
propensity score
protein binding
Protein Binding
quasi experimental study
signal transduction
steady state
stochastic model
Stochastic Processes
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