Viral surface geometry shapes influenza and coronavirus spike evolution through antibody pressure
The evolution of circulating viruses is shaped by their need to evade antibody response, which mainly targets the viral spike. Because of the high density of spikes on the viral surface, not all antigenic sites are targeted equally by antibodies. We offer here a geometry-based approach to predict an...
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| Format: | Article |
| Language: | English |
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Public Library of Science
2021
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| Online Access: | View Fulltext in Publisher |