Effect of fixed orthodontic appliances on nonmicrobial salivary parameters

Objectives: To examine possible changes in the levels of salivary antioxidants, C-reactive protein (CRP), cortisol, pH, proteins, and blood in patients treated with fixed orthodontic appliances. Materials and Methods: Salivary samples from 21 orthodontic patients who met specific inclusion criteria...

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Bibliographic Details
Main Authors: Ginsburg, I. (Author), Gorelik, S. (Author), Koren, E. (Author), Shalish, M. (Author), Zogakis, I.P (Author)
Format: Article
Language:English
Published: Allen Press Inc. 2018
Subjects:
pH
Online Access:View Fulltext in Publisher
LEADER 02836nam a2200517Ia 4500
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008 220706s2018 CNT 000 0 und d
020 |a 00033219 (ISSN) 
245 1 0 |a Effect of fixed orthodontic appliances on nonmicrobial salivary parameters 
260 0 |b Allen Press Inc.  |c 2018 
856 |z View Fulltext in Publisher  |u https://doi.org/10.2319/111317-773.1 
520 3 |a Objectives: To examine possible changes in the levels of salivary antioxidants, C-reactive protein (CRP), cortisol, pH, proteins, and blood in patients treated with fixed orthodontic appliances. Materials and Methods: Salivary samples from 21 orthodontic patients who met specific inclusion criteria were collected before the beginning of orthodontic treatment (T0; baseline), 1 hour after bonding (T1), and 4-6 weeks after bonding (T2). Oxidant-scavenging ability (OSA) was quantified using a luminol-dependent chemiluminescence assay. Cortisol and CRP levels were measured using immunoassay kits. pH levels and presence of proteins and blood in the samples were quantified using strip-based tests. Results: A significant decrease in salivary pH was observed after bonding (P ¼ .013). An increase in oxidant-scavenging abilities during orthodontic treatment was detected, but the change was not statistically significant. Cortisol and CRP levels slightly increased after bonding, but the difference was small without statistical significance. Changes in the presence of proteins and blood were also insignificant. Conclusions: Exposure to fixed orthodontic appliances did not show a significant effect on salivary parameters related to inflammation or stress, with the exception of a significant but transient pH decrease after bonding. © 2018 by The EH Angle Education and Research Foundation, Inc. 
650 0 4 |a adolescent 
650 0 4 |a Adolescent 
650 0 4 |a Antioxidants 
650 0 4 |a C reactive protein 
650 0 4 |a case control study 
650 0 4 |a Case-Control Studies 
650 0 4 |a chemistry 
650 0 4 |a C-Reactive Protein 
650 0 4 |a dental bonding 
650 0 4 |a Dental Bonding 
650 0 4 |a female 
650 0 4 |a Female 
650 0 4 |a human 
650 0 4 |a Humans 
650 0 4 |a hydrocortisone 
650 0 4 |a Hydrocortisone 
650 0 4 |a Hydrogen-Ion Concentration 
650 0 4 |a male 
650 0 4 |a Male 
650 0 4 |a Orthodontic Appliances, Fixed 
650 0 4 |a pH 
650 0 4 |a Prospective Studies 
650 0 4 |a prospective study 
650 0 4 |a saliva 
650 0 4 |a Saliva 
650 0 4 |a saliva protein 
650 0 4 |a Salivary parameters 
650 0 4 |a Salivary Proteins and Peptides 
700 1 |a Ginsburg, I.  |e author 
700 1 |a Gorelik, S.  |e author 
700 1 |a Koren, E.  |e author 
700 1 |a Shalish, M.  |e author 
700 1 |a Zogakis, I.P.  |e author 
773 |t Angle Orthodontist