Evidence for Non-Essential Salt Bridges in the M-Gates of Mitochondrial Carrier Proteins

Mitochondrial carriers, which transport metabolites, nucleotides, and cofactors across the mitochondrial inner membrane, have six transmembrane α-helices enclosing a translocation pore with a central substrate binding site whose access is controlled by a cytoplasmic and a matrix gate (M-gate). The s...

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Bibliographic Details
Main Authors: Di Noia, M.A (Author), Miniero, D.V (Author), Monné, M. (Author), Palmieri, F. (Author), Palmieri, L. (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher