A Promising Way to Overcome Temozolomide Resistance through Inhibition of Protein Neddylation in Glioblastoma Cell Lines

There is no effective therapy for the lately increased incidence of glioblastoma multiforme (GBM)—the most common primary brain tumor characterized by a high degree of invasiveness and genetic heterogeneity. Currently, DNA alkylating agent temozolomide (TMZ) is the standard chemotherapy. Nevertheles...

Full description

Bibliographic Details
Main Authors: Berta, G. (Author), Brandt, B. (Author), Heffer, M. (Author), Németh, M. (Author), Pap, M. (Author), Rauch, T.A (Author), Szünstein, M. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
Online Access:View Fulltext in Publisher
View in Scopus