A Promising Way to Overcome Temozolomide Resistance through Inhibition of Protein Neddylation in Glioblastoma Cell Lines
There is no effective therapy for the lately increased incidence of glioblastoma multiforme (GBM)—the most common primary brain tumor characterized by a high degree of invasiveness and genetic heterogeneity. Currently, DNA alkylating agent temozolomide (TMZ) is the standard chemotherapy. Nevertheles...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI
2023
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Subjects: | |
Online Access: | View Fulltext in Publisher View in Scopus |