Synthesis of novel bisindolylmethane Schiff bases and their antibacterial activity

Synthesis of novel bisindolylmethane Schiff bases and their antibacterial activity

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In an effort to develop new antibacterial drugs, some novel bisindolylmethane derivatives containing Schiff base moieties were prepared and screened for their antibacterial activity. The synthesis of the bisindolylmethane Schiff base derivatives 3-26 was carried out in three steps. First, the nitro...

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Bibliographic Details
Main Authors: Hussain, M. (Author), Imran, S. (Author), Ismail, N.H (Author), Khan, K.M (Author), Naz, F. (Author), Taha, M. (Author), Tauseef, S. (Author)
Format: Article
Language:English
Published: MDPI AG 2014
Subjects:
1,1-bis(3'-indolyl)methane
4-nitrophenyl
Antibacterial
Anti-Bacterial Agents
antifungal agent
Antifungal Agents
antiinfective agent
benzaldehyde derivative
Benzaldehydes
Bisindole Schiff base
Bisindolylmethane
chemistry
drug effects
Gram negative bacterium
Gram positive bacterium
Gram-Negative Bacteria
Gram-Positive Bacteria
human
Humans
indole
Indole
indole derivative
Indoles
Nickel acetate
nitrophenol
Nitrophenols
Schiff base
Schiff Bases
Sodium borohydride
synthesis
triazole derivative
Triazoles
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