All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells
All-trans-retinoic acid (ATRA) has been clinically used to treat acute promyelocytic leukemia and is being studied to treat other types of cancer; however, the therapeutic role and mechanism of ATRA against cholangiocarcinoma (CCA) remain unclear. The present study investigated the cytotoxic effect...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Spandidos Publications
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |