Comparative evaluation of different bone markers in peri-implant crevicular fluid of immediate loaded and nonloaded dental implants

Aim: The present study was conducted to determine different bone markers in immediate loaded and nonloaded dental implants. Materials and methods: It comprised of 60 patients (males-30, females-30) which were divided into two groups of 30 each. Group, I received immediate loaded dental implants, and...

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Bibliographic Details
Main Authors: Kumar, V. (Author), Rana, M. (Author), Sharma, P. (Author), Subhas, S. (Author), Tiwari, A. (Author), Ul Haque, M.I (Author)
Format: Article
Language:English
Published: Jaypee Brothers Medical Publishers (P) Ltd 2018
Subjects:
Online Access:View Fulltext in Publisher
LEADER 03393nam a2200661Ia 4500
001 10.5005-jp-journals-10024-2429
008 220706s2018 CNT 000 0 und d
020 |a 15263711 (ISSN) 
245 1 0 |a Comparative evaluation of different bone markers in peri-implant crevicular fluid of immediate loaded and nonloaded dental implants 
260 0 |b Jaypee Brothers Medical Publishers (P) Ltd  |c 2018 
856 |z View Fulltext in Publisher  |u https://doi.org/10.5005/jp-journals-10024-2429 
520 3 |a Aim: The present study was conducted to determine different bone markers in immediate loaded and nonloaded dental implants. Materials and methods: It comprised of 60 patients (males-30, females-30) which were divided into two groups of 30 each. Group, I received immediate loaded dental implants, and group II received non-loaded dental implants. Modified bleeding on probing index, peri-implant sulcus depth was assessed in both groups at 1 month, 2 months, 3 months and 4 months. The crevicular fluid was obtained to determine bone markers levels such as transforming growth factor-alpha (TGF-α), osteocalcin (OCN), osteopontin (OPN), parathyroid hormone (PTH) and osteoprotegerin (OPG). Results: Both groups revealed non- significant difference in modified bleeding on probing index and peri-implant sulcus depth (p > 0.05). Bone markers found to be elevated more in group I as compared to group II. However, the difference was non- significant (p > 0.05). Conclusion: Transforming growth factor alpha (TGF-α), OCN, OPN, OPG and PTH and parathyroid hormone (PTH) levels were higher in immediate loaded dental implants as compared to nonloaded dental implants. Clinical significance: Immediate loaded dental implants showed an increase in expression of bone markers such as TNF-α, OCN, OPN, PTH and OPG which may be useful in deciding future of immediate loaded dental implants. © Jaypee Brothers Medical Publishers (P) Ltd. 
650 0 4 |a biological marker 
650 0 4 |a Biomarkers 
650 0 4 |a Bone markers 
650 0 4 |a comparative study 
650 0 4 |a Crevicular fluid 
650 0 4 |a Dental Implantation 
650 0 4 |a Dental Implants 
650 0 4 |a female 
650 0 4 |a Female 
650 0 4 |a genetics 
650 0 4 |a Gingival Crevicular Fluid 
650 0 4 |a gingivitis 
650 0 4 |a human 
650 0 4 |a Humans 
650 0 4 |a Immediate Dental Implant Loading 
650 0 4 |a Immediate loaded dental implants 
650 0 4 |a male 
650 0 4 |a Male 
650 0 4 |a metabolism 
650 0 4 |a middle aged 
650 0 4 |a Middle Aged 
650 0 4 |a osseointegration 
650 0 4 |a Osseointegration 
650 0 4 |a osteocalcin 
650 0 4 |a Osteocalcin 
650 0 4 |a osteopontin 
650 0 4 |a Osteopontin 
650 0 4 |a osteoprotegerin 
650 0 4 |a Osteoprotegerin 
650 0 4 |a parathyroid hormone 
650 0 4 |a Parathyroid Hormone 
650 0 4 |a physiology 
650 0 4 |a procedures 
650 0 4 |a time factor 
650 0 4 |a Time Factors 
650 0 4 |a tooth implant 
650 0 4 |a tooth implantation 
650 0 4 |a transforming growth factor alpha 
650 0 4 |a Transforming Growth Factor alpha 
700 1 |a Kumar, V.  |e author 
700 1 |a Rana, M.  |e author 
700 1 |a Sharma, P.  |e author 
700 1 |a Subhas, S.  |e author 
700 1 |a Tiwari, A.  |e author 
700 1 |a Ul Haque, M.I.  |e author 
773 |t Journal of Contemporary Dental Practice