A method for identification of inhibitors of the phosphorylation reactions of bacterial response regulator proteins using 31P nuclear magnetic resonance spectroscopy
Bacterial response regulators are attractive targets for antibacterial drug development, yet random screening against these targets has failed as yet to identify chemicals that constitute viable leads. Alternative methods to provide leads for drug development based on identification and optimization...
Main Authors: | Hubbard, Julia A. (Author), MacLachlan, Lesley K. (Author), Johnson, Peter (Author), Findlow, Stuart C. (Author), Ladds, Joanne C. (Author), Lewis, Ceri J. (Author), Carter, Paul S. (Author), Jones, Jo J. (Author), Fosberry, Andrew P. (Author) |
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Format: | Article |
Language: | English |
Published: |
2001-12-01.
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Subjects: | |
Online Access: | Get fulltext |
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